Chronic cystitis with bladder disorders

Symptoms

The symptoms related with glycosaminoglycans (GAGs) layer loss in the bladder wall are predominately those of bladder irritation.8

The symptoms range from mild to severe and intermittent to constant. Symptoms can vary from person to person and may include the following:

  • Pain, irritation, pressure, discomfort or other unpleasant sensation related to the urinary bladder.6

    Pain could be the hallmark symptom; it worsens with specific foods or drinks or as the bladder fills and gets better with urination. People can experience both acute and chronic pain:

    • Acute pain: has a sudden beginning and lasts for a shorter time period
    • Chronic pain: recurs frequently or lasts for a longer time period
  • FREQUENT NEED TO URINATE.6

    Person needs to urinate more frequently than normal during the daytime and at night (up to 60 times a day in severe cases).6

  • URGENT NEED TO URINATE.6

    Need to urinate immediately due to increasing pain, pressure, or spasms and may be accompanied by a feeling of stress, malaise and/or nausea.6

The diagnosis normally involves a thorough medical history and physical examination and requires further investigation by a consultant urologist.6

6. Jane M. Meijlink R, editor. Interstitial Cystitis/Bladder Pain Syndrome: Diagnosis & Treatment. IPBF Publication. 2014. 8. Damiano R, Cicione A. The role of sodium hyaluronate and sodium chondroitin sulphate in the management of bladder disease. Ther Adv Urol. 2011;3(5):223-32.