Chronic cystitis with bladder disorders

Classification of cystitis

Bladder Pain Syndrome / Interstitial Cystitis (BPS/IC)

BPS / IC patients can have persistent or recurrent symptoms of pain, pressure, or discomfort related to the bladder, usually accompanied by a frequent and urgent need to urinate day and night.3

While the symptoms may resemble a urinary tract infection, there is no infection to be seen in the urine.

Recurrent Bacterial Cystitis (RBC)

Bacterial cystitis is an inflammation of the bladder usually caused by bacteria entering the bladder via the urethra. It can sometimes be referred to as a urinary tract infection (UTI).4

If repeated recurrent bacterial infections occur i.e. three or more urinary infections per year, this is classed as recurrent bacterial cystitis (RBC).4


Some cancer treatments may cause irritation in the bladder (hemorrhagic cystitis) as a side effect, specifically, administration of treatments directly into the bladder, or radiation therapy to the pelvic region (radiation induced cystitis (RIC)).5

3. Sorensen R. Chondroitin Sulphate in the Treatment of Interstitial Cystitis and Chronic Inflammatory Disease of the Urinary Bladder. European Urology Supplements 2, 2003, 16-18.
4. COB Foundation. Cystitis Handbook: The Cystitis & Overactive Bladder Foundation 2012.
5. Shao Y, Lu GL, Shen ZJ. Comparison of intravesical hyaluronic acid instillation and hyperbaric oxygen in the treatment of radiation-induced hemorrhagic cystitis. BJU international. 2012;109(5):691-4.